Early detection of cancer.
2023-05-22
However, the current methods for urine-based BC detection have significant levels of false-positive signals.
In this study, we report on uAL100, a method to precisely detect BC tumor DNA in the urine without tumor samples.
The mutations identified in the urine DNA by uAL100 for BC detection were highly associated with BC tumorigenesis and progression.
We suggest that uAL100 has improved accuracy compared to other urine-based methods for early BC detection and can reduce unnecessary cystoscopy tests for patients with hematuria.