Through a simple blood draw, key genes related to various cancer types of solid cancers (including gastric, lung, colon, breast, liver, pancreatic, ovarian and uterine cancer, as well as rare cancers such as melanoma and sarcoma) can be tested for somatic mutations.
2. Accurate
In-depth analysis using the latest AlphaLiquid® bioinformatics analysis
CancerCheck delivers fast and accurate results based on IMBdx’s robustly validated, machine-learning enabled and patented AlphaLiquid® bioinformatics pipeline for genomic data analytics.
Recommended for
1. Suspected cancer risk diagnosis (e.g., increase in cancer markers)
2. Cancer survivors (e.g., during follow-up after cancer treatment)
3. High-risk groups (e.g., family history of cancer)
CancerCheck Test Process
Blood Sampling
Easy collection of blood
30mL of blood is sampled for the CancerCheck test.
The blood is stored in dedicated cfDNA tubes.
Genetic Analysis
Genetic mutation analysis using AlphaLiquid’s latest bioinformatics pipeline
cfDNA in the blood is extracted and amplified to run Next Generation Sequencing and subsequent AlphaLiquid® analysis to detect mutations.
Clinical Report
Results delivered in 3 weeks
The results are delivered in a report which includes information on genetic mutations, its characteristics, and descriptions of target genes.
Features of CancerCheck
Diversified Analysis of Shift Patterns
Detects all major types of genomic alternations including Single nucleotide variants (SNVs), Insertions & Deletions (Indels), Copy Number Alterations (CNAs), Fusions, as well as key genomic signatures such as Microsatellite Instability (MSI), Tumor Mutation Burden (TMB), Loss of Heterozygosity (LOH)
Advantages to Tissue Biopsy
It can be difficult or sometimes impossible to collect a sufficient sample for a tissue biopsy, depending on the size and location of the tumor.
· CancerCheck test conducted through a convenient blood draw.
Advantages to other blood-based cancer marker tests
Blood cancer markers (e.g., CEA, CA-19-9, PSA) can be increased without there actually being cancer, resulting in high false positives and poor accuracy.
· CancerCheck directly analyzes cfDNA derived from tumor cells which enables accurate testing for various genomic alternations and signatures.
Advantages to other blood-based cancer marker tests
Blood genetic tests are for used for hereditary cancer-related (germline) mutations, and their accuracy and specificity can be compromised as they are limited in detecting somatic mutations.
· CancerCheck is based on the clinically validated AlphaLiquid® 100 panel which consists of carefully selected, high-frequency cancer-related genes applicable to most types of solid cancers to produce more specific and sensitive test results.
